The pathway would be over active, If a ligand were stuck in the G-protein-linked receptor.
<h3>What usually happens when a ligand binds to a receptor protein?</h3>
When the ligand attached to the internal receptor, a change occurs that shows at DNA-binding site on the protein.
The ligand-receptor complex moves into the nucleus where it binds itself to regions of the chromosomal DNA. It promotes the initiation of the process of transcription so we can conclude that if a ligand were stuck in the G-protein-linked receptor, the pathway would be over active.
