According to the chemiosmotic hypothesis, ATP is produced by due to the proton gradient created across the mitochondrial membrane. The essential components required for chemiosmosis are proton pump, proton gradient and ATP synthase. ATP synthase is an enzyme which helps in ATP synthesis. The enzyme ATP synthase has two part
F0 andF1.F0 is the part which transports protons across the membrane as a transmembrane channel while configuration changes in F1
activates the enzyme. They phosphorylate ADP i.e., add one more phosphorus group to the ADP and converts ADP(adenosine diphosphate) to ATP (adenosine triphosphate). The proton gradient developed across the membrane is the driving force of ATP synthase.
