Question

The regulatory protein responsible for binding to calcium for contraction to proceed is _____.

Answer 1

The regulatory protein in muscle responsible for binding to calcium for contraction to proceed is troponin.

Troponin is a crucial player in the regulation of muscle contraction by calcium: The actin-tropomyosin-troponin complex, which makes up the thin filaments of striated muscles, is the only structure that can bind calcium. Actin filaments are also connected to troponin, a calcium-binding protein that controls contraction in skeletal or cardiac muscles.

Three parts or subunits of troponin:

• Tropomyosin-binding subunit (Tn-T)
• Inhibitory subunit (Tn-I)
• calcium-binding subunit are the  (Tn-C)

NMR spectroscopy was used to determine the atomic structure of the troponin head.Troponin and tropomyosin are both necessary for the control of calcium in striated muscles. Troponin or tropomyosin mutations result in the well-known cardiac myopathy.

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