Epimysium, perimysium, and endomysium interrelated at the muscle's surface, the perimysium network and epimysium are joined. Another continuous network structure, the endomysium, is located between individual muscle fibers within each fascicle or fiber bundle.
Whole muscles are encased in the epimysium. The perimysium, which is connected to the epimysium, separates muscular fiber groups into fasciculi. Individual muscle fibers are encircled by a delicate network of connective tissue fibers, blood arteries, lymphatic vessels, and nerves known as the endomysium.
The collagen fibers of tendons are made of endomysium, perimysium, and epimysium, providing the tissue link between muscles and bones by indirect attachment.
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