Answer:1.) solute too large for channels
2.) solute not lipid soluble
3.) solute not able to move down concentration gradient.
Answer: whats the letters to answers
Explanation:
The activation energy of a given chemical reaction is the minimum required amount of energy needed to start the reaction, for the reaction to start. All reactions have an activation energy, even spontaneous ones, ones that do occur spontaneously. It is a thermodynamic barrier that separates the amount of energy reactant molecules must possess to ultimately react with each other to produce the respective products.