Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
DNA.
Explanation:
Type II restriction endonucleases always cleave at or near their recognition sites. They produce small, well-defined fragments of DNA that help to characterize genes and genomes and that produce recombinant DNAs.
The correct answer to this question is epistemological and prototype theory
Gettier contributed to what we know about the epistemological<span> model of truth </span>while Rosch contributed to what we know about the prototype theory model. Eleanor Rosch is a professor of psychology at the University of California, Berkeley while Edmund L. Gettier III is an Professor Emeritus at the University of Massachusetts Amherst<span>. He is also an American Philosopher.</span>
1. Intensity.
2. Duration of shaking.
3. Nature of material upon which structure rests.
4. Nature of building materials and the construction practices of region.
