In arteriosclerosis, overproduction of abnormal collagen and decreased quantities of elastin lead to Decreased coronary artery perfusion.
Arteriosclerosis is a condition in which the arteries, which transport oxygen and nutrients from the heart to the rest of the body, thicken and stiffen, often limiting blood flow to the organs and tissues. Flexible and elastic arteries indicate good health. However, the artery walls can stiffen over time, a phenomenon known as arterial hardening.
The accumulation of lipids, cholesterol, and other chemicals in and on the artery walls is known as atherosclerosis. The accumulation is known as plaque. Atherosclerosis can constrict the arteries and obstruct blood flow. The plaque may rupture and cause a blood clot.
Symptoms of arteriosclerosis:
- chest pressure or discomfort (angina)
- sudden numbness or weakness in the arms or legs.
- speech slurs or speaking difficulties.
- vision briefly lost in one eye.
- weakened facial muscles
- ache while walking.
- elevated blood pressure
- renal failure
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