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podryga [215]
1 year ago
12

Januvia, the trade name for sitagliptin, was introduced in 2006 for the treatment of type 2 diabetes. In what type of orbital do

es the lone pair on each n atom reside.
Medicine
1 answer:
Paladinen [302]1 year ago
8 0

In the following orbital the lone pair on each N atom is present:

N1: sp3,

N2: p,

N3: p,

N4: sp2,

N5: sp2

Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.

The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.

The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.

Here is another question with an answer similar to this about Sitagliptin: brainly.com/question/28275161

#SPJ4

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Here is how Lydia found the product 4/5 x 10. Use the model given to show that Lydia's answer is correct.
Veseljchak [2.6K]

Answer: Lydia's answer is correct.

Explanation:

The solution used by Lydia is:

4/5 × 10 = 4 × 1/5 × 10

= 4 × 10/5

= 4 × 2

= 8

The above solution by Lydia is correct.

Given the question, 4/5 × 10, this will be:

= 4/5 × 10/1

Let's multiply the numerator first, this will be: = 4 × 10 = 40

The denominator will be: = 5 × 1 = 5

Therefore, 4/5 × 10/1 = 40/5

Now when we divide 40 by 5, we will get 8. Therefore Lydia is correct.

4 0
3 years ago
Outline THREE points you would use in a discussion on the reasons for outbreak of violent behaviour among spectators or players
Serggg [28]
The importance of the result (money, position in league or competition, team rivalry)
the nature of the game (contact sports are more likely to lead to violence, for example ice hockey versus bowls)
provocation (crowd chanting abuse, 'sledging' by other players)
7 0
3 years ago
Read 2 more answers
1. Suppose that asthma affects 1 in 20 children in a population. You take a simple random sample of 300 children from this popul
uysha [10]
Answer: 15

Explanation: since it affects only 1 out of 20, you can divide 300 by 20 which equals 15
4 0
2 years ago
a client with a terminal illness who is incapacitated is experiencing intractable pain that is no longer effectively addressed b
arlik [135]

The nurse anticipates using palliative sedation to handle this client's intractable pain.

<h3>How does the term "intractable pain" mean in medicine?</h3>

The definition of debilitating pain is "hardship whose source can indeed be removed and, per the broadly agreed clinical practice, a wide spectrum of pain treatment modalities adequate for this patient have been used without sufficient result or with unacceptable side effects." When a health care professional certifies a patient as having severe chronic pain, they were also certifying that the patient fulfills this definition.

<h3>An intractable function is what?</h3>

When considering computational complexity, intractable issues are those for which there are no effective solutions. The brute-force search algorithm is the one that offers a solution to the majority of seemingly insoluble situations.

To know more about intractable pain visit :

brainly.com/question/8507609

#SPJ4

4 0
1 year ago
Read 2 more answers
Blood PC02 may be measured by:
Vikentia [17]

Blood PC02 may be measured by using direct spectrophotometer

Explanation:

Blood gas analysis or arterial blood gas (ABG) test is done to determine blood pH and the amount of oxygen and carbon dioxide dissolved in arterial blood.

Blood PCO2 is the partial pressure of carbon dioxide dissolved in the arterial blood.

ABG or oximetry test is done by using direct spectrophotometry in a spectrophotometer and gas analysis is done by calorimetric methods. Spectrophotmetry is highly used in Medicine to perform quantitative analysis of blood and its composition. The spectrophotometer measures the light intensity or wavelengths absorbed by the sample solution.  

Blood PCO2 reflects the degree of exchange gases in and out of the lungs. An increase in PCO2 levels indicates respiratory illnesses like obstructive lung diseases or pulmonary edema; while a decrease indicates conditions like hypoxia, pulmonary embolism, hyperventilation etc.

3 0
3 years ago
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