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podryga [215]
1 year ago
12

Januvia, the trade name for sitagliptin, was introduced in 2006 for the treatment of type 2 diabetes. In what type of orbital do

es the lone pair on each n atom reside.
Medicine
1 answer:
Paladinen [302]1 year ago
8 0

In the following orbital the lone pair on each N atom is present:

N1: sp3,

N2: p,

N3: p,

N4: sp2,

N5: sp2

Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.

The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.

The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.

Here is another question with an answer similar to this about Sitagliptin: brainly.com/question/28275161

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lutik1710 [3]

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Read more about the health journal:

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8 0
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charle [14.2K]

Answer:

Taking into account that:

The flow velocity u of a fluid is a vector field

u = u (x, t)

What gives the velocity of a Fluid Plot at position x y time t.

q = || u ||

Now if the flow is continuous as it happens in the blood vessels then:

The flow of a fluid is said to be constant if it does not move over time, that is why the variant would be 0.

Explanation:

As for the pump with narrow vessels, there the area would be less, therefore the flow also and the flow velocity as well. Adding that the friction with the walls increases as it is narrower, thus generating an increase in pressure with the flow of the liquid.

So this is where we have to put emphasis on the biophysics branch that explains the following:

The Venturi effect is explained by the Bernoulli Principle and the principle of continuity of mass. If the flow rate of a fluid is constant but the section decreases, the speed necessarily increases after crossing this section. By the theorem of conservation of mechanical energy, if the kinetic energy increases, the energy determined by the value of pressure necessarily decreases.

Indeed, according to Bernoulli's principle:

P 1 + 21 ρv 12 + ρgh 1 = P 2 + 21 ρv 22 + ρgh 2

I don't know

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Answer:

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Explanation:

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kykrilka [37]

Answer:

Explanation:

ames Brantner had always been scrupulous about maintaining his health. He sees his primary care doctor annually, avoids sweets and developed a habit of walking 3.5 miles every other day near his home just outside Harrisburg, Pennsylvania.

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Allisa [31]

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To prevent the risk, one should Manage your diabetes, monitor your blood sugar level and also keep BP and cholesterol under control.

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