The metabolism of cyclophosphamide results in a number of metabolites having alkylating action. Phosphoramide mustard and acrolein were the main metabolites found. Dephosphoramidation of phosphoramidated mustard can produce nornitrogen mustard, which also possesses alkylating properties.
<h3>What safety precautions should be considered when working with chemotherapy medications?</h3>
Personnel should be protected from exposure when handling HDs by using personal protective equipment (PPE). PPE consists of respiratory barrier protection, gloves, gowns, goggles for eye protection, and a complete face shield for head protection.
Frequently, cyclophosphamide produces nausea, vomiting, and appetite loss. Even if you start to feel sick, it's crucial that you keep taking the medication. Without first consulting your doctor, do not discontinue using this medication. For advice on how to decrease these symptoms, ask your doctor.
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