The most important reason for the collapse of Rome was the failure to actually integrate what they conquered. When Roman soldiers conquered new lands, it was rare that they ever attempted to force their culture, ideals, or laws upon the natives and barbarians. Thus, when the Empire began suffering internal struggles, the natives they had conquered decided to take action, which lead to the swift collapse by barbarian invasion from all sides. It's hard to pick a LEAST important reason, seeing that there were many of them, but I suppose a contender would most likely be the common refusal of the Empire to even acknowledge that barbarians were rising. On the outer edges of their territory, in places like Gaul and Morocco, the Roman government was reluctant to even recognize the threat of the barbarians, thinking that even accepting that these barbarians were causing trouble would weaken their prestige in the public eye.
When cash is contributed to a political party with no limits attached to the amount that can be received, this is known as a "soft money<span>" contribution.</span>
The significance was that these allowed goods to be transported much faster than by horse. Canals allowed for things to be imported and exported much more easily.