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erma4kov [3.2K]
1 year ago
6

Wnts play an important role in promoting emt in developing neural crest progenitors. what is the receptor for secreted wnts?

Social Studies
1 answer:
Anvisha [2.4K]1 year ago
7 0

The receptor for the secreted Wnts is Frizzled.

Frizzled proteins are receptors for secreted Wnt proteins, as well as other ligands, and also play a critical role in the regulation of cell polarity during embryonic development. The frizzled genes were first identified in Drosophila in a screen for mutations that disrupt the polarity of epidermal cells in the adult fly.

Frizzled proteins also play key roles in governing cell polarity, embryonic development, formation of neural synapses, cell proliferation, and many other strategies in developing and person organisms. those processes occur because of one in every of three signaling pathways.

These include the canonical Wnt/β-catenin pathway, Wnt/calcium pathway, and planar cellular polarity (PCP) pathway. Mutations within the human frizzled-4 receptor were related to familial exudative vitreoretinopathy, an extraordinary disease affecting the retina in the back of the attention, and the vitreous, the clean fluid internal the eye.

Learn more about proteins here: brainly.com/question/10058019

#SPJ4

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