Yes, there were five states that joined the Union in war, but I do not think they were ten years apart.
Answer:
Within a short period of time their way of life was changed forever. The changes were caused by a number of factors, including loss of land, disease, enforced laws which violated their culture and much more. When the Europeans arrived they brought with them diseases unknown to the natives.
Traveling to and from cities became easier. (I think thats correct)
The Byzantines spread Christianity mostly by sending out missionaries for the Greek Orthodox Church.
In general, it was an increase in the service industry that led to a decline in labor union membership, since many of these workers don't need representation.