RAS is a very important protein that belongs to a class of protein referred to as GTPases and plays a crucial role in switching on pathways that control cell growth, proliferation, apoptosis and differentiation and migration. For RAS to become inactive it must hydrolyze GTP to GDP which slows down the process of cell proliferation. Mutation in one copies of RAS will result to cancer because the mutated copy will permanently attach to GTP and remain in activated form which will lead to uncontrollable cell division and hence development of cancer.
Answer: Nucleus membrane isn't part of the ER or Golgi Apparatus, BUT all of them are part of the endomembrane system.
Endoplasmic reticulum and Golgi apparatus are two membrane-bound organelles found in eukaryotes. Both these organelles are closely associated and functionally related. Both endoplasmic reticulum (ER) and Golgi apparatus are two components of the endomembrane system of a cell. Lysosomes and vesicals are the other components of the endomembrane system.
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Key is to lock as D. Substrate is to active site.
