Answer:
1 point ok my dear friends
La luna está en el espacio.
"the moon is in space"
<span>a ellos no _les____ importa el itinerario</span>
<h3>El paciente tiene las manos __.</h3>
Answer: cerradas
El paciente tiene las manos cerradas.
Translation: The patient has his hands closed.
Explanation:
"Manos" is a feminine and plural noun, so its adjective must agree in gender and number with this noun. "Manos cerradas".