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kicyunya [14]
3 years ago
15

Identify the structures of the heart.

Biology
1 answer:
bija089 [108]3 years ago
7 0

Answer:

i have put an image for a diagram of the heart in the answers becuase you did not provide a diagram so i hope this helps

Explanation:

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Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis. Cell Death Differ. 2020,
vovangra [49]

Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.

Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.

However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.

meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.

We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.

Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.

Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.

Learn more about breast cancer here : brainly.com/question/6747562

#SPJ4

4 0
2 years ago
Fill in the blank<br> ___diffision involves transport proteins
stellarik [79]

Answer:

Facilitated diffusion involves transport protein

Explanation:

4 0
3 years ago
What is a quantitative observation? A. An observation that proves the hypothesis is wrong. B. An observation about the number or
Ghella [55]
The answer is B An observation about the number or amount of something
8 0
3 years ago
Which of the following correctly sequences the steps of the scientific method?
Minchanka [31]

Answer:

observe, question, make a testable explanation, experiment, collect and analyze data, state findings

Explanation:

5 0
3 years ago
Convert 86,000 cm to km. Show all of your work.
Dominik [7]
Centimeter = 1/100 of a Meter
Kilometer = 1000 Meters

86,000/100 = 860 Meters
860/1000 = 0.86 Kilometers
3 0
3 years ago
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