Bioaccumulation refers to the accumulation of a toxic chemical in the tissue of a particular organism.
Biomagnification refers to the increased concentration of a toxic chemical the higher an animal is on the food chain.
Answer:
<em>Backyard bird feeding is a well known </em><em>type of human–untamed life </em><em>communication in specific regions of the northern and southern side of the equator.</em>
Explanation:
In territories where sustaining is mainstream in the Southern Hemisphere, supplemental encouraging may excessively profit acquainted winged creature species while driving with decreases of local species, possibly due to hetero specific competition.
However, Backyard bird feeders can bring about constructive outcomes on some feathered creature species, for example, improved overwinter endurance, expanded populace sizes and geographic range extension.
<span>it is a polysaccharidee </span>
Answer:
Exosomes as Therapeutic Target
Given the fact that elevated exosome levels are often correlated with greater severity of different types of cancer, reducing circulating exosomes to normal levels is one of therapeutic strategies to increase treatment efficacy. There are different approaches to modulate exosome production: 1) Inhibition of exosome formation: inhibit crucial proteins involved in exosome formation pathway; 2) Inhibition of exosome release: inhibit important regulators of exosome release process, increased intracellular Ca2+, change cellular microenvironmental pH; 3) Inhibition of exosome uptake: add proteinase for surface proteins on exosomes may serve as receptors for uptake pathways. In addition to control exosomes production, removal of exosomes from the entire circulatory system might be a novel strategy for cancer treatment.
Exosomes could also be used as cancer immunotherapy becasue tumor-derived exosomes carry antigens that is a great source of specific stimulus for the immune response against tumors. Both tumor-derived and dendritic cell-derived exosomes have showed capability to stimulate tumor antigen-specific responses in experimental animal models and human clinical trials.
Exosomes as Targeted Drug Delivery Vehicles
Exosomes became one of the most common methods applied in drug delivery system because of several advantages they have. Firstly, exosomes normally have a small size 40-100 nm, which is more homogenous compared to other microvesicles. This will lead them to evade rapid clearance by the mononuclear phagocyte and enhances passage through fenestrations in the vessel wall. Secondly, due to their endogenous origin, they are less toxic for and better tolerated by the immune system. It facilitates them to avoid causing side effects that normally occur with synthetic nanoparticles. Additionally, the specific ligand or protein expressed on the exosome surface increases efficiency of cargo into the cytosol of the target cell, and therefore fewer off-target effects. Exosomes are generally found most useful as a drug delivery medium in cancer therapy, anti-inflammation and gene interference therapy such as transferring of miRNA.
There are different kinds of cargos encapsulated by exosomes, especially like siRNA or miRNA. The delivery of RNA is attracting because they are rapid degradation in cell circulation and have the limitation in passing through the membrane and in cellular uptake. Chemotherapeutics loaded into exosomes is also used for cancer therapy such as doxorubicin. In principle, there are four key components to achieve correct functionality and efficacy during exosomes drug delivery:1) Choosing the donor cell type to produce drug-carrying exosomes; 2) Using correspond methods to encapsulate the exosomes cargo; 3) Enhancing the specificity of cargo delivery by targeting peptides on the surface of the exosomes; 4) Administrating exosomes to target the area of disease.
Explanation:
https://www.creative-biostructure.com/exosome-applications-652.htm
Answer:
Dominant
Explanation:
A hybrid trait is also known as heterozygous, which is the combination of the dominant and recessive alleles of a gene. On the other hand, a purebred is combination of the same two dominant alleles or the same two recessive alleles. For example, in the gene coding for height, allele for tallness (T) is dominant over the allele for shortness (t).
A purebred for this trait will either be "TT" or "tt" while a heterozygous or hybrid will be Tt. Hence, according to this question, crossing of a hybrid (Tt) and a dominant purebred (TT) will always result in offspring which are DOMINANT (see attached image).
