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andrew11 [14]
4 years ago
13

Explain how the structure of cholesterol enables it to perform structural and functional roles within membranes

Biology
1 answer:
Umnica [9.8K]4 years ago
7 0
The plasma membrane is a continuous double layer of phospholipids which are intertwined with the help of cholesterol and proteins. Cholesterol is an amphipatic molecule, meaning it has a hydrophilic and hydrophobic portion. A part of the steroid ring is closely attracted to the fatty acid chains on the phospholipids which helps to immobilize the outer surface of the membrane. 

Cholesterol also helps to build the lipid rafts that secure the proteins while passing through membrane canals, so it participates in the process of information exchange between the cells.
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3 years ago
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where they execute important functions. The polypeptide chain of these proteins must cross the lipid bilayer. This presents a pr
spin [16.1K]

Answer:

In this case, it is likely that the polypeptide chain assumed an alpha helix configuration because the lipid bilayer did not have beta-barrel proteins.

Explanation:

A polypeptide chain is naturally polar, however, a lipid bilayer is naturally non-polar. This makes it difficult and even prevents the polypeptide chain from crossing a lipid bilayer, since the composition of these two elements does not allow them to mix. In that case, the polypeptide chain has two options to take to successfully cross the lipid bilayer.

The first option that the polypeptide chain has is to allow the creation of twisted beta sheets in the shape of a closed barrel in its structure. This only works if the lipid bilayer has beta barrel proteins in its composition to act as a transport channel for the polypeptide chain. However, few lipid layers have this protein.

Most likely, the polypeptide chain assumes an alpha helix conformation to cross lipid bilayers that do not have beta-barrel proteins. By assuming the beta conformation, the polypeptide chain reinforces the hydrogen bonds present in its composition, allowing it to cross the lipid bilayer without having its conformation and structure disassembled.

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3 years ago
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5 0
4 years ago
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