OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
Sequence is extremely important when it comes to A. chronological order.
Chronological order means that you are writing events in the exact order in which they occurred. Obviously, this is where sequence comes in, because sequence of events refers to the way, or order in which they actually happened. Thus, sequence is important for chronology, and doesn't have much to do with cause and effect, compare and contrast, or examples and explanations.
Answer:
When Milo asks it to wait, he answered with his weight.
Explanation:
This bird has untidy feathers, long beaks and grey. It liked chaos and was a nuisance. Ironically, he is from a place called context and yet he likes to take every speech out of context. He twists what people say.
As an example in this story, after the bird flies away, Milo shouts at it to wait but the bird replied out of context by saying thirty four pounds which is weight.
Answer:
Cheating is never the answer.
Every bad thing comes with a cost
Explanation: i hope that helped
