Answer:
2 i think .... soooooooo confusing
Explanation:
As I think your question is incomplete .So sorry I am unable to give the answer.Plse rectify the question.
<span>According to the NIMH, 20% of the people with autism spectrum disorders also have genetic disorders such as Fragile X syndrome, Down syndrome and / or tuberous sclerosis.</span>
Because all enzymes are specific in nature therefore the must fit to their specific substrates so if the shape is changed it might not fit perfectly to it's substrate.