Is composed of G1 phase<span> (</span>cell<span> growth), followed by S </span>phase<span> (DNA synthesis), followed by G2 </span>phase<span> (</span>cell<span> growth). At the end of interphase comes the mitotic </span>phase<span>, which is made up of mitosis and cytokinesis and leads to the formation of two daughter </span>cells<span>.
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Hemoglobin SS and sickle beta zero thalassemia are the most severe forms of sickle-cell disease and are sometimes referred to as sickle cell anemia. Hemoglobin SC disease is considered moderate and in general, sickle beta plus thalassemia is the mildest form of sickle-cell disease.
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Answer:
The purine ring is built onto ribose-5-phosphate of PRPP for its de-novo nucleotide biosynthesis, while the ring structure of the pyrimidine bases are synthesized separately and then coupled to ribose-5-phosphate via the C-N glycosidic bond.
Explanation:
In the de novo synthesis of nucleotides, their metabolic precursors such as aminoacids, ribose-5-phosphate, CO₂ and NH₃ are used as starting materials.
In purine nucleotide synthesis, the ring structure is built up on ribose-5-phosphate of PRPP by addition of one or a few atoms one at a time starting with the amino group donated by glutamine until the first intermediate inosinate is synthesized.
In pyrimidine ring synthesis, orotate is first synthesized from carbamoyl phosphate and aspartate, and then is attached to ribose-5-phosphate of PRPP, before it is then converted to the common pyrimidine nucleotides starting from uridylate.
Many different species of blue-green algae occur in lakes
