I think the answer should be clay :)
The EOP agency that directly relates to domestic affair is :
Office of Policy development
Office of Policy Development is responsible in advising and assisting president in the formulation, coordination, and implementation of domestic and economic policies.
Historically, they burned the people infected with it(to death if not already dead)
I believe that one was it could only request states for funds. The government under the articles had hardly any power.