In astronomy, the interstellar medium (ISM) is the matter and radiation that exist in the space between the star systems in a galaxy. This matter includes gas in ionic, atomic, and molecular form, as well as dust and cosmic rays. It fills interstellar space and blends smoothly into the surrounding intergalactic space
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I believe that the answer is negative space.
Fresco Secco. In the dry plaster or "fresco secco" technique, pigments are usually mixed with water, although other substances might also be used. The paint is then applied to a dry plaster wall which has been wetted down with water.