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Federalism is a mixed or compound mode of government that combines a general government (the central or "federal" government) with regional governments (provincial, state, cantonal, territorial or other sub-unit governments) in a single political system.
It does not apply to executive orders.
It only applies to the choice of people for certain offices, such as ambassadors and federal judges: the Senate can advice the president in this choice and needs to consent to the president's decision.
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"On April 22, 1793, President George Washington issued a Neutrality Proclamation to define the policy of the United States in response to the spreading war in Europe. “The duty and interest of the United States require,” the Proclamation stated, “that they [the United States] should with sincerity and good faith adopt and pursue a conduct friendly and impartial toward the belligerent Powers.” The Proclamation warned Americans that the federal government would prosecute any violations of this policy by its citizens, and would not protect them should they be tried by a belligerent nation. [...]"
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