Interstitial growth is the type of growth that occurs within cartilage and results in bone elongation.
It occurs because chondrocytes are capable of dividing and form a cluster of two to four or more cells in a gap.
These groups of chondrocytes are known as isogenic groups or cell nests and they increase the cartilage from within.
In this process it happens because they descend from other chondrocytes that have undergone several mitotic divisions and continue dividing.
Once cytoplasmic constriction occurs in dividing cells, a septum of intercellular substance develops between them, separating the daughter cells.
In this way, interstitial growth develops two types of dispositions:
- If mitosis is carried out in only one direction, we have a group of aligned chondrocytes (axial isogenic group).
- If the divisions are carried out in all directions, we have a coronary isogenic group.
In the epiphyseal lines of long bones, the cell division of chondrocytes occurs in one plane, resulting in the ordering of long columns, which are subsequently invaded by bone tissue.
The division of the chondrocytes and the secretion of a new matrix between the cells, gives rise to a bone elongation of the cartilage from the inside.
Therefore, we can conclude that interstitial growth is the type of growth that occurs within cartilage and results in bone elongation.
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