Question

Predict the effect of aldosterone hypo secretion on body fluid pH.

Answer 1

Answer:

Aldosterone is the hormone produced by the adrenal cortex, aldosterone is a hormone that inhibits the level of sodium excreted in the urine, maintaining volume and blood pressure.

Explanation:

Several hormonal systems regulate the urinary and intestinal excretion of potassium, so that its activation can produce hypokalemia, and its hyperkalemia blockade.

The most important hormonal axis is the renin angiotensin aldosterone (SRAA) system and the β-adrenergic hormones. In addition to increasing the renal excretion of potassium and the secretion of this cation by the salivary, sweat glands and the intestine, aldosterone can also favor the entry of potassium into the cell.

Aldosterone increases distal sodium reabsorption and potassium secretion. Aldosterone secretion by the adrenal glands is stimulated in hyperkalemia and is inhibited in hypokalemia.

Aldosterone modulates renal excretion of potassium:

- Increasing the intracellular concentration of potassium by stimulating the activity of the Na-K-ATP-Basolateral pump

- Increasing the density and activity of the ENaC channel

- Increasing the expression of ROMK channels