I would say histamine, a chemical in the body associated with immune responses. It causes the itch and redness you see with insect bites, rashes and skin dryness or damage.Histamine<span> is released by the body during allergic reactions, such as those to </span>pollen<span>, food, </span>latex<span> and </span>medications<span>.
Itching is activated by a chemical called histamine. It's associated with our immune system. It is what causes the red marks and itching from bug bites.