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Native Americans were vulnerable during the colonial era because they had never been exposed to European diseases, like smallpox, so they didn’t have any immunity to the disease, as some Europeans did.
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Explanation:
Yet there are also setbacks that accompany U.S. imperialism. American colonization is destroying the culture of indigenous peoples who have forgotten their identity and tradition. In certain cases, indigenous residents grow up to discriminate against what is local and originally their own native community.
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The Great Compromise solved the problem of representation because it included both equal representation and proportional representation. The large states got the House which was proportional representation and the small states got the Senate which was equal representation.