In act 5, Scene 8, Macduff was found to be taken out of his mothers womb prematurely. Due to this, He was not "born a female." This was significant because witches told Macbeth he could not be slain by a man born of a female. Therefore Macduff is Macbeth's killer.
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When reading Act 5, Scene 8 , you learn how Macduff was taken from his mothers womb untimely. Thus he was not "born a woman". This is noteworthy since the witches said to him that he was not able to be killed by anyone born of a woman. Accordingly it turns out to be Macduff who kills macbeth.
