He sent the U.S. Navy and Marines to fight the pirates and protect American ships and trading, which resulted in the Barbary War. In 1801 pirates captured American sheeps, demanding America pay tribute to the Barbary rulers, and Jefferson refused to give any cent which lead to War.
Pretty sure the answer is China and Egypt
It was a way of making sure they weren't followed or shot in the arce as they were running away
It was the "Open Door Policy" that was the name of the trading policy that Secretary of State John Hay initiated with China and the European nations that already had a presence there, since the US wanted to benefit from trade with China as well.