the Spanish Empire would expand across the Caribbean Islands, half of South America, most of Central America and much of North America (including present day Mexico, Florida).For the most part, treated the Native Americans poorly. The Spanish were interested in the riches of the Americas, and they had no problem in forcing the Native Americans into slavery so they could mine the gold and the silver for Spain. The Spanish wanted to convert the Native Americans to Christianity.
The plague came from the fleas on the rats and the rats traveled through ships and merchants ship coming from other countries. Once the rats with the fleas reached a city heavily populated, mass amounts of people died because the disease was contagious. To add to that the cities were extremely dirty and had dead people everywhere.
Scott Joplin was the one who pioneered classical ragtime music.