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RoseWind [281]
3 years ago
5

What second messenger most directly causes calcium ions to be released from intracellular stores?

Biology
1 answer:
NemiM [27]3 years ago
6 0

Answer: adenylyl cyclase inositol triphosphate mainly known as IP3 causes the release of Calcium ions directly from the inracellular stores and causea contraction.

Explanation:

IP3, inositol phosphate is a second messenger a signaling molecule. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by an enzyme phospholipase C.

IP3 binds to the calcium channels and opens Ca2+ channels that are embedded in the ER membrane, releasing Ca2+ into the cytosol. Calcium ions released may cause contraction and regulate the Ca2+ channels in the membranes.

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6 0
3 years ago
Cystathioninuria can be caused by two different mutations in the enzyme cystathionase. Cystathioninuria caused by mutation 1 can
polet [3.4K]

Answer:

C. The enzyme with mutation 1 has decreased affinity for pyridoxal phosphate, whereas the enzyme with mutation 2 has lost the ability to bind to the substrates.

Explanation:

A coenzyme is an organic cofactor that binds with an enzyme in order to initiate or aid the function of the enzyme. A coenzyme binds to the active site of the enzyme (where the reaction occurs), thereby triggering its activation by modifying protein structure during the reaction. Some examples of coenzymes include Coenzyme A and Adenosine triphosphate (ATP). Pyridoxal phosphate is a coenzyme (it is the active form of vitamin B6) that is required for the function of cystathionase. Moreover, cystathionase is an enzyme that enables cells the synthesis of cysteine from methionine (transsulfuration pathway). The binding of pyridoxal phosphate to the enzyme increases the binding affinity of the enzyme for the substrate, thereby influencing its activity. In this case, it is expected that mutation 1 reduces the binding affinity of the enzyme to the cofactor, and thereby the cofactor is required at a higher concentration to restore normal enzyme activity.

3 0
3 years ago
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ANEK [815]
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Hope it helped,



BioTeacher101

6 0
3 years ago
Read 2 more answers
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