Most of the mutations have no effects whatsoever on the organisms but some can be dangerous. There are two types of mutations that cause harm to the organism's ability to survive:teratogen muations are the mutations that form inside the uterus when the fetus is still developing and can even kill it or cause severe malformations that lead to death in the early life. Carcinogen mutations are the ones that lead to the formation of neoplasms(masses of cells that divide uncontrollably, basicly cancer).
As the left ventricle contracts, oxygenated blood leaves the heart through the aortic valve, into the aorta. The blood to lower limb flows through descending aorta, which continues down to Left Common Femoral Artery, which continues down to Left Superficial Femoral Artery, which continues down to Left Popliteal Artery. The Left Popliteal Artery gives 2 divisions.
1. Left Tibioperoneal Artery (which continues down to the Left Posterior Tibial Artery which supplies back of the foot.)
2. Left Anterior Tibial Artery (which continues down to Left Dorsalis Pedis Artery which continues down to <em>Left First Dorsal Metatarsal Artery</em> which supplies the big toe/first digit of foot.)
If they show signs of shock, are hemorrhaging, say that they are experiencing one, etc.