Question

Descriptions of enzyme mechanisms often contain the terms intermediate, transition state, and transition state analogue. The terms intermediate and transition state both describe chemical species along the reaction pathway, but there are important distinctions between the two. Transition state analogues are often used in enzyme mechanism studies. Match each phrase to the term that it describes.

Answer 1

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Answer:

The transition state is the state that has highest activation energy as compared with the reactant or product. Intermediate state is important for the conversion of the reactant into the product. Transition state analogue may be any molecule that has similar feature with the transition state.

The intermediate state has the finite life time greater than the 10⁻¹³s.They can be detected easily as well as stable. Intermediate stages include the enzyme substrate complex or enzyme product complex. Transition state analogue mimic the transition state and can also acts as inhibitor. The transition state shows highest energy and o not have fix life time. The incomplete broken bonds and incomplete formed bonds are present in the transition state.