Question

Clinical research may be disease oriented or patient oriented, explain the differences and when you would use each one.

Answer 1

Answer:

Patient-oriented: performed on humans with direct contact between the patient and the investigator.

Disease-oriented: identify molecules and cells linked to a disease.  

Explanation:

Clinical research is a study conducted on humans, design to develop techniques and create knowledge. It involves several activities orientated to test a hypothesis and draw conclusions about diseases.

Patient-oriented clinical research is a specific type of clinical study with humans, that requires an interaction between the patient and the investigator.  This research is performed to detect, treat and prevent human diseases as well as understand the disease's mechanism to develop technologies and create knowledge in this field. For example creating a less invasive technique to treat a patient, heart assist devices, vaccines, inhaled medicine for pulmonary problems and cellular therapies.

Disease-oriented clinical research is a study that seeks to understand molecular or cellular features that are linked to human diseases to identify their response to treatment. For example identify cancer target molecules, use of genes and proteins for the diagnosis and treatment of cardiovascular diseases, stem cells to treat autoimmune diseases and genetic therapies to treat molecular and cellular problems.