The wording to this question is a little confusing.
detrimental well being since detrimental means to causing harm. But i believe that you mean what are two factors to a well being in a relationship. In that case: 1. good communication, that is very important in all types of relationships.
2. would be trust, and the ability to relay on the other for support and vice versa
Il ne mange que de la nourriture verte comme le brocoli
If you can not remove it adapt to it and learn to live with it