Answer:
Cancer cells such as Hela cells escape to normal cell cycle by mutations that lead to the misexpression and/or overexpression of regulatory molecules (e.g., cyclins and cyclin-dependent kinases) and faulty checkpoint control of the cell cycle
Explanation:
The term cell cycle refers to the mechanism of DNA replication and cell division, which involves a series of sequential steps. The control of the cell cycle depends on 1-cyclins and cyclin-dependent kinases (CDKs) that regulate the cell cycle by a cascade of protein phosphorylations and 2- a group of checkpoint controls that monitor the completion of critical cellular events. HeLa is an immortalized cell line derived from cervical cancer cells. These cells (HeLa) contain 76 to 80 total chromosomes (instead of the 46 chromosomes that contain normal-diploid body cells), some of which are heavily mutated. These mutations can affect CDKs that control the cell cycle as well as checkpoint-control mechanisms (for example, those resulting from DNA damage), thereby cells do not enter programmed cell death (apoptosis) and proliferate uncontrollably.
It is often useful for scientists to study a population of cells that are all at the same stage of the cell cycle.
<h3>Why the discovery of cyclins and cdks was enabled?</h3>
The discovery of cyclins and cdks was enabled by studying frog eggs that divided synchronously after fertilization; extracts from the embryos were thus representative of the cell-cycle stage at which the extract was made.
Researchers have devised means to synchronize asynchronous populations of cultured cells. for example, serum starvation deprives cells of mitogens and blocks cells in the g0/g1 phase of the cell cycle.
Therefore, It is often useful for scientists to study a population of cells that are all at the same stage of the cell cycle.
Learn more about cell cycle on:
brainly.com/question/15876101
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Answer: seen below
Explanation:
In vigorous exercise, your brain and body do everything they can to cool you off by increase the flow of blood to the skin where it can cool down with the aid of sweating , while in someone who has an infection they push the temperature inside your body to extreme levels by strengthening your immune system resistance to the infection, the immune system deliberately raises your body temperature as part of its strategy to kill the infection attacking you.
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