Cystic fibrosis and chronic bronchitis both are a <u>chronic obstructive pulmonary disease</u>. These disorders are characterized by increasing breathlessness Goblet cells in the lungs are responsible for the extra production of mucus. It plays an essential role in the <u>protection of the mucous membrane</u>.
Further Explanation:
Goblet cells lie in the epithelium lining of the airways that conducts respiration. The vital function of cell is to produce mucus which provides protection to the epithelium by covering it with gel like substance. The mucus produced by these cells is comprises from mucin and inorganic salt. <u>Mucins are the glycosylated protein</u>. They are found in the electrolyte solution.
Mucus is secreted by irritating stimuli which is produced <u>by exocytoses process</u> and helps in the determination of the efficiency of entrapment and transportation of inhaled irritants, particles as well as microorganisms. Mucin <u>is found in the intracellular granules</u> of the goblet cells.
Goblet cells secrete mucus in response to several stimuli such as proteinases, irritant gases, inflammatory mediators, and reactive oxygen species.
In normal conditions, the goblet cells tend to proliferate and differentiate into ciliated cells and help in the maintenance of airway epithelial cell population. T cell mediated immunity is also modifies by goblet cell secretion.
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Answer Details:
Grade: Senior School
Subject: Biology
Chapter: Respiration and breathing disorders
Keywords:
Lungs, respiration, goblet cells, ciliated cells, oxygen, carbon dioxide, stimuli, mucus, epithelial cells, gglycosylated, electrolyte, exocytoses, immunity.