Answer:
D keep the proceedings secret and abandon the Articles of Confederation.
Explanation:
The metropolitan area is a large population center consisting of one large metropolis and the surrounding area, or several neighboring central cities and the surrounding area. One or more big cities can act as a hub, and metropolitan areas are usually named according to the biggest or most important central city in them. An example is the Jabodetabek Metropolitan Area, where Jakarta is the core city and "Bodetabek" as the surrounding buffer zones have interdependent relations. Metropolitan is an urban system which means a collection of cities interacting and working together to achieve certain goals in a complex environment.
Each enzyme has an "active site". The active site of each enzyme is unique in terms of 3D structure. Each unique active site can be thought of as a 3D surface that is able to bind only a single unique substrate or set of substrates, and it is the shape of the active site that is responsible for each enzyme's substrate selectivity. Most enzymes actually use the same or nearly the same, mechanisms of action; most commonly simple acid-base chemistry is used to catalyse reactions.
It may be difficult to understand, but enzyme active sites are actually thought to bind the "transition state" of the substrate. The transition state may be thought of as a state where the structure of the substrate is literally stretched to be somewhere between the orginal substrate structure, and the structure of the product of the enzyme catalyzed reaction. In other words, the enzyme can be thought of as "pulling" the substrate into a product. In this way, the enzyme lowers the energy required to pass the "transition" state, and accelerates the reaction of substrate to product.
Thus, the structure of the enzyme imparts both its substrate specificity (because only certain substrates will fit into the active site), and its activity (because in binding the substrate, the enzyme lowers the transition energy required for the substrate to form product).
Hope this helped, despite my rambling.
Answer:
The Battle of Waterloo was in 1815. It was fought in the present-day province of Waterloo Brabant, Belgium.
Explanation:
The Battle of Waterloo is acknowledged as the end of the Napoleonic Wars (1803-1815), the set of wars led by Bonaparte in his expansionist attempts in Europe. He aimed to establish France hegemony on the continent and to spread the French Revolution ideals throughout the region.
It was Bonaparte's preparation in 1803 for these future wars that led him to sell the French territories in North America to the newly independent United States. The event became known as Louisiana Purchase.
