Question

A Mateo y Marta ______ duelen los ojos. nos te le les

Answer 1

Answer:

A Mateo y Marta les duelen los ojos

Explanation:

Mateo y Marta is third person plural, so we need to use "les". "nos" can only be used for first person plura, "te" for second person singular and "le" for third person singular. The noun always gives you a clue as to the correct for to use the verbs.

Answer 2

Según yo la forma correcta de decirlo es:
A Mateo y Marta les duelen los ojos.