The first sentence is an interrogatory question, so a question mark is used. The second sentence is a declarative sentence and will use a period. The third sentence is an exclamatory sentence, and should use an exclamation mark at the end.
I’m assuming this is a punctuation question. The correct way would be: Christopher Columbus, born in Genoa, never did reach mainland North America. There should be a comma before and after “born in Genoa”.
