Use a comma before any coordinating conjunction (and, but, for, or, nor, so, yet) that links two independent clauses.
"to friends" = prepositional phrase
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Here is the answer that would best complete the given statement above. IRBS reviewing research in a different geographical location and/or cultural context have a responsibility to d<span>efer to an IRB that is in the situated within the local research context and ask specialists with direct knowledge of the local research context to participate in IRB discussions. Hope this answers your question.</span>
