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DedPeter [7]
3 years ago
10

TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessiv

e tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene?
Biology
1 answer:
Umnica [9.8K]3 years ago
6 0

Answer:

Explanation:

Since it is a recessive gene, tumor suppressor genes required the inactivation of both alleles, this is usually accomplished by the mutation of one allele and a targeted homozygous deletion of the second allele. This leads to an effective inactivation of the suppressor genes with the mutations acting a a dominant negatives. This way, patients are put at a higher risk of developing cancer

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