The chromosomal defect is caused when I part of a chromosome breaks off at either end attaches to another chromosome is called Translocation.
The puppies heads are often to big to fit through their mothers birth canal. They may get birth defects like flat chests, if their face are wrinkly they get acne and eye problems, and they are prone to skeletal disorders like hip dysplasia.
Breathing, moving blood throughout the body, and so forth.
