Cancers are said to be caused by genetics, meaning the disease originated from the DNA structure. There are viruses that affect the DNA. Examples are hepatitis B virus, Epstein-Barr virus, herpes virus-8 and human papilloma virus. These are the DNA viruses that could cause cancer.
Well, an endoskeleton is an internal skeleton, like humans have.
Pro: Bones do not get broke as easily, since they are inside of the body. Bones that break also heal more quickly in an endoskeleton, since they have tissue and blood surrounding it and transferring nutrients.
Con: The flesh can get easily damaged. There is no shedding with endoskeletons, so a new skeleton cannot be grown in the event of an injury.
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The answer u r looking for is- D* failure of the immune system to distinguish self from nonself. Hope I’ve helped ;)