The statement that w<span>hen combined with alcohol or other depressant drugs, the depressant effect of antihistamines can be much greater is true. If you consume alcohol while taking drugs or antidepressant medicates, their effect will be greater. The effect of the alcohol on the drugs depends on their structure and purpose. Because both alcohol and depressant drugs have sedative effect of the body, the depressant effect will be much greater.</span>
