Insulin is produced by a type of cell called a Beta-Cell which is located in the pancreas. When over production or underproduction or no production is noted, then it is an indication that some sort of metabolic illness involving beta cells is present. These are usually diseases such Diabetes Mellitus both I and II,Prediabetes, Gestational Diabetes (mostly diabetes)
Lower resting heart rates indicate cardiovascular fitness. Though lower resting heart rates can also be a sign of a disease or condition, such as bradycardia, generally, it's better to have a lower resting heart rate, as it's a sign of a healthy heart.