Usually punctuation and capitialization...
The thing that happen between chapter 21 and chapter 22 is the tone permanently changes to a more cynical attitude and this is the significant structural shift. The answer to this question is which asking about what happen between chapters 21 and 22 is that the tone permanently changes to a more cynical attitude.
Answer:
time order, sequence vocabulary
Explanation:
Ex.
next
then
after that
later
....