The answer is; A & C
The lagging strand is replicated in fragments called Okazaki fragments, each initiated by a primer. The fragments are later joined into one strand by DNA ligase. Replication occurs by adding nucleotides to the 3’ end of a preceding nucleotide. Because the lagging strand is antiparallel to the leading strand, the replication of the lagging strand is in the opposite direction as the replication fork direction. This is why the lagging strand is replicated in fragments because replication is being carried out by a single DNA polymerase (moving in the direction of the replication fork) per replication fork.
The molecule C-P phosphorylates and thus activates D, whereas Kinase D amplifies cellular signaling by phosphorylating many substrates. In this case, it is expected to observe kinase D overexpression in Brec-MUT cells.
<h3>Cancer, phosphorylation and signaling pathways</h3>
Cancer can be defined as a multifactorial disease, which is often associated with uncontrolled cell growth.
Cancer signaling may be associated with defective pathways such as, for example, a mutated kinase protein that affects normal downstream molecular cascades.
A kinase is a specific protein that acts to phosphorylate specific cellular substrates, thereby activating/deactivating a particular signaling pathway.
Learn more about cancer pathways here:
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Answer:
protons and neutrons
Explanation:
Protons and neutrons have a positive and neutral charge, respectively. They are in the nucleus, while the negative electrons orbit the nucleus.
Food and nutrition are fundamental to military capability. Historical examples demonstrate that a failure to supply adequate nutrition to armies inevitably leads to disaster; however, innovative measures to overcome difficulties in feeding reap benefits, and save lives. In barracks, UK Armed Forces are currently fed according to the relatively new Pay As You Dine policy, which has attracted criticism from some quarters. The recently introduced Multi-Climate Ration has been developed specifically to deal with issues arising from Iraq and the current conflict in Afghanistan.Answer:
Explanation:
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