Jews. Because they went through a lot.
I'm interested in this question myself, I don't think Indians ever left physical structures behind, so I looked up a ton on geographical features left behind by Indians and not just in Northeastern and Southeastern America, because there are many types of Indians, but nothing came up on any type of Indian especially in the 1500's. I tried, but I don't think this question can be answered, I looked up this question in many different ways and broke it down to try and gather small pieces of information, but in the end there was no features known to be left behind by American Indians. If anything they left behind culture and methods of doing things. Hope anything I said helps even though I could not figure out the answer.
Answer: Causes: Renaissance encouraged curiosity, investigation, discovery, modern day knowledge. Caused people to question old beliefs. During the era of the Scientific Revolution, people began using experiments and mathematics to understand mysteries.
Effects: New discoveries were made, old beliefs began to be proven wrong
Explanation:
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I googled it lolol your welcome