In distance, it's something like maybe 245,000 miles ... corresponding to the several Apollo missions during which a Command and Service module entered lunar orbit and swung around the back side of the moon with astronauts aboard.
The farthest from Earth that a human has ever gone <em>and walked on solid ground</em> is roughly 238,000 miles, corresponding to the six Apollo missions that landed six pairs of astronauts on the near side of the surface of the moon, between 1969 and 1972 .